Mycobacterium
tuberculosis the causative agent of tuberculosis
(TB) still the major killer among human population, that has co-evolved with
the human civilization so beautifully and so robustly, is really surprising.
The war against tuberculosis is on and we are trying here to integrate major
resources that are available for the disease and the organism all over the web
to a single place. This is one of the open articles that would be upgraded time
to time for acknowledging the recent development in the field, so that you as a
used need not spend much time in data collection and integration. Hope this
helps.
General
information about tuberculosis:
Wiki
page on tuberculosis on
Wikipedia: http://en.wikipedia.org/wiki/Tuberculosis
Tuberculosis, MTB, or TB (short for tubercle bacillus) is a common, and in many cases
lethal, infectious disease caused by various strains of mycobacteria,
usually Mycobacterium tuberculosis.
Tuberculosis usually attacks the lungs but can also affect other parts of the body. It is spread
through the air when people who have an active MTB infection cough, sneeze, or otherwise
transmit their saliva through the air. Most infections in humans result in an asymptomatic,
latent infection, and about one in ten latent infections eventually progress to
active disease, which, if left untreated, kills more than 50% of those
infected.
Wiki
page on M. tuberculosis: Mycobacterium
tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium
and the causative agent of most cases of tuberculosis
(TB). First discovered in 1882 by Robert Koch,
M. tuberculosis has an unusual, waxy coating on its cell surface
(primarily mycolic acid), which makes the cells impervious to Gram staining,
so acid-fast
detection techniques are used, instead. The physiology of M. tuberculosis
is highly aerobic and requires high levels of oxygen.
Primarily a pathogen of the mammalian respiratory system, MTB infects the lungs. The
most frequently used diagnostic methods for TB are the tuberculin skin test,
acid-fast stain, and chest radiographs. The M. tuberculosis genome was sequenced in
1998.
Centers for Disease Control and Prevention
(CDC) page on tuberculosis:
Tuberculosis (TB) is a disease caused by a bacterium called Mycobacterium
tuberculosis. The bacteria usually attack the lungs, but TB bacteria can
attack any part of the body such as the kidney, spine, and brain. If not
treated properly, TB disease can be fatal. TB disease was once the leading
cause of death in the United States. Focusing on Data and Statistics, Diseases
and Conditions, Emergencies and Disasters, Environmental Health, Healthy Living,
Injury, Violence and Safety, Life Stages and Populations, Travelers' Health, Workplace
Safety and Health, Learn More »
Global
TB database: http://www.who.int/tb/country/global_tb_database/en/index2.html
Access the database to make data queries,
interactive maps and country profiles. Country profiles: Country
profiles provide key indicators, notification and treatment outcome data, and
budget and financing graphs (for a subset of countries, including all
high-burden countries). For high-burden countries, there is also a brief
overview of TB control and epidemiology in the country, and a summary of
achievements, challenges and planned activities related to implementing the
first 5 components of the Stop TB Strategy.
U.S. National
Library of Medicine Resource on tuberculosis: Has a resourced on various fields of the
disease, from the basics to the advanced including the disease data.
WHO
page on tuberculosis: Too many people have undetected TB
for too long; late detection of TB increases their risk of transmitting the
disease to others, having poor health outcomes, or that they and their family
will suffer distress and economic hardship. WHO has produced an overview of
approaches, guidelines and tools to improve early detection of TB. It presents
a framework to assess barriers for early detection and helps identify
appropriate actions.
The
Stop TB Partnership: The Stop TB Partnership is leading
the way to a world without tuberculosis (TB), a disease that is curable but
still kills three people every minute. Founded in 2001, the Partnership's
mission is to serve every person who is vulnerable to TB and ensure that
high-quality treatment is available to all who need it. Together our nearly
1000 partners are a collective force that is transforming the fight against TB
in more than 100 countries. They include international and technical
organizations, government programmes, research and funding agencies,
foundations, NGOs, civil society and community groups and the private sector. We
operate through a secretariat hosted by the World Health Organization (WHO) in
Geneva, Switzerland and seven working groups whose role is to accelerate
progress on access to TB diagnosis and treatment; research and development for
new TB diagnostics, drugs and vaccines; and tackling drug resistant- and
HIV-associated TB. The secretariat is governed by a coordinating board that
sets strategic direction for the global fight against TB.
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